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Energy, porphyrin, and neurotransmitter homeostasis are the key metabolic pathways affected by heavy metal exposure, potentially implicated in the pathogenesis of ASD

Neuroprotection 121, 2024, Elmahboub YSM, Elkordy AA

Mechanism: Alpha-lipoic acid appears to enhance glucose uptake by activating AMP-activated protein kinase (AMPK), a master metabolic regulator, and by improving insulin receptor signaling

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The level of palmitoylated V5_GSTP1 (neutravidin-HRP) relative to total V5_GSTP1 was expressed as a % of the 48 h time point