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Matrix molecules and skin biology

Reuteman-Fowler et al

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus

Collectively, the data indicate that compound R3 is particularly effective in inhibiting inflammation mediated by prostaglandins and leukotrienes, while showing limited activity against histamine- and bradykinin-induced responses

doi: 10.1016/j.cmet.2019.06.016 31 WenZJinKShenYYangZLiYWuBet al

Alcohol reduces glutathione levels in the liver, which can lead to liver cell injury and contributes to the development of alcoholic liver disease (Lieber 2003)