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As recent studies have suggested that preeclamptic trophoblasts are highly likely to undergo glycolytic reprogramming, the newly discovered TLR4/NF-B/PFKFB3 pathway may function as a link between metabolic reprogramming and NLRP3 inflammasome induced trophoblast apoptosis (102)

Efferocytosis fuels requirements of fatty acid oxidation and the electron transport chain to polarize macrophages for tissue repair