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Mechanobiology of Macrophages: How Physical Factors Coregulate Macrophage Plasticity and Phagocytosis

As a result, the ETC functioning is disrupted, and ATP content becomes significantly depleted, which breaks down metabolic and ionic homeostasis and activates the degradative enzymes such as nucleases, proteases, and phospholipases [182, 188]

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C.ChakiM.Sanchez-CalvoB.Mata-PerezC.LeterrierM.PalmaJ

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Lipid bilayer was placed at centre in a rectangular periodic box filled with TIP3P water and ZIL (with 8716 and 32 molecules, respectively), where the buffer size between the edges of the box and the lipid model was set at around 34 , and the MD simulation of cell membrane in 5 wt% ZIL aqueous solution was carried out using Amber18 and AmberTools19 software 31