The second component t (2) clearly showed the minor impact of vB12 on WT compared with the Tbx1 +/ (compare filled dots with filled triangles)

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Folic Acid: Prevents folate deficiency, which can lead to anemia, birth defects, and neurological issues
Although a fairly large proportion of patients have reported a number of side effects, particularly at the gastrointestinal level (nausea, vomiting, diarrhoea), these side effects tend to diminish over time and adherence to treatment remains high, with about 5% of patients discontinuing treatment due to side effects
It can be the same as other nutritional deficiencies
While vitamin B12 deficiency is common and well-understood, elevated B12 levels can occasionally occur