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10.1136/gut.2010.232025 Gut

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The intention is to raise awareness of the impact of AMD on public health, review the current understanding of the pathobiology of this disease, offer future research directions that focus on unbiased systems approaches, encourage the continued efforts of dedicated vision scientists who focus on dry AMD, and encourage the broader scientific community to join in a collaborative effort to develop therapies for this complex and debilitating disease

There are many glaucoma cases, for example, where the IOP is in the normal or even below normal range, but negative changes continue to occur in vision, similar to if the IOP remained higher than normal

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CNS diseases Many CNS diseases are attributed to hyperactivity of neurons or unregulated neuronal cell death