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doi: 10.3390/ijms222212403 35 ConradMPrattDA

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Under cystine deprivation stress, GBM cells can upregulate GGT1 expression and utilize alternative pathways to maintain GSH homeostasis, thereby preventing the occurrence of ferroptosis ( 5.4 Safety and selectivity challenges in ferroptosis therapy Achieving tumor-specific ferroptosis induction while preserving normal tissues, particularly brain function, is a core challenge for clinical translation

Tripathi PN, Srivastava P, Sharma P, Tripathi MK, Seth A, Tripathi A, Rai SN, Singh SP et al (2019) Biphenyl-3-oxo-1,2,4-triazine linked piperazine derivatives as potential cholinesterase inhibitors with anti-oxidant property to improve the learning and memory