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Irisin protects against sepsis-associated encephalopathy by suppressing ferroptosis via activation of the Nrf2/GPX4 signal axis

Biochem Pharmacol 146:112610 Karthika C, Appu AP, Akter R, Rahman M, Tagde P, Ashraf GM, Abdel-Daim MM, Abid A, Bungau S (2022) Potential innovation against Alzheimers disorder: a tricomponent combination of natural antioxidants (vitamin E, quercetin, and basil oil) and the development of its intranasal delivery

Blood 62(Suppl 1):204a, 1983

83 Oxidation of BH 4 not only reduces BH 4 bioavailability but also the oxidation products such as BH 2 may compete with BH 4 for binding to eNOS, 90 thereby leading to eNOS uncoupling

Analytic tools that take into account the medical work up, such as RUCAM, should be used to further delineate the likelihood of causation

The digested sample was then distilled using an N310 semi-automatic Kjeldahl nitrogen analyzer (Gerhardt, China) and titrated with 0.5 mol/L H 2 SO 4 until the gray-red endpoint was observed