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ThSpositive signals were visualized under an epifluorescence microscope

Front Aging Neurosci 11:435469

6.2 Drug-induced GS status Various drugs can affect key enzymes in bilirubin metabolism, resulting in mildly elevated serum bilirubin levels (mimicking a GS state) ( Figure 6 )

TG(33:0e) + NH4 also reduces inflammation and oxidative stress in the context of RAGE inhibition

Benzo[a]pyrene significantly increases the incidence of hyperplasia and adenomas in female A/J mice in a dose-dependent manner

It is reported that SA could reduce neuroinflammation, oxidative stress and cell apoptosis in cerebral ischemia-reperfusion injury, thereby ameliorating brain tissue damage, which may be involved in its inhibitory effect on excessive endoplasmic reticulum stress (54) indicated that SA could directly bind to the conserved cysteine residue 140 (Cys140) of IMPDH2, and further lead to IMPDH2 inactivation, thereby suppressing neuroinflammatory responses