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Garca-Revilla J, Ruiz R, Espinosa-Oliva AM, Santiago M, Garca-Domnguez I, Camprub-Ferrer L, Bachiller S, Deierborg T, Joseph B, de Pablos RM, Rodrguez-Gmez JA, Venero JL (2024) Dopaminergic neurons lacking Caspase-3 avoid apoptosis but undergo necrosis after MPTP treatment inducing a Galectin-3-dependent selective microglial phagocytic response

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Annu Rev Cell Dev Biol 27: 441464, 2011 [DOI] [PubMed] [Google Scholar] 57

Therefore, in states of chronic under-nutrition, hepatic GH resistance is an adaptive response, as high GH levels are necessary to maintain euglycemia, while low IGF-I levels conserves energy during periods of nutritional deprivation