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This decrease in mutant p53 levels contributes to extended survival

although the exact reason for this is unclear (Aspuru 2011

We treated monolayers of either BJ fibroblasts or HuVEC endothelial cells with TZ, T-DM1 and T-DXd for seven days and measured survival by MTT assays

Donzanti BA, Yamamoto BK (1988)

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Still pointed out that a notable feature in many of these cases of moral defect without general impairment of intellect is a quite abnormal incapacity for sustained attention