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Additional investigation is required to better define subtle between-chemotherapy agent differences in the pathogenesis of CIPN as a means for enhancing rational discovery of novel treatments with potential to prevent and/or attenuate the development of CIPN

Skin and energy benefits usually appear after 48 weeks

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PMID: 9 ChangIWLinVCHungCHWangHPLinYYWuWJet al

[DOI] [PubMed] [Google Scholar] 48.Csiszr J., Brunner S., Horvth E., Bela K., Kdmn P., Riyazuddin R., Gall ., Hurton ., Papdi C., Szabados L., et al

The presence of eNOS results in greater dilation of the blood vessel and less stress on the vascular wall