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Nevertheless, metal oxide doses administrated at 1mg/kg in a single dose need proper safety profile investigation for use in clinical settings [187]

The study of Meguid et al., involved 30 healthy children and 30 children affected by autism (18 males, 12 females), aged 311 years, all diagnosed with DSM-V and CARS, with no reported medical comorbidities and in good physical health

As a critical biological component of the upper respiratory tract (URT) mucosal barrier, URT microbiota plays a fundamental role in maintaining local immune homeostasis and reinforcing barrier defenses against environmental pathogens 95,96

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A small study from Islamabad on a clinical population of patients with megaloblastic anemia reported figures of 76% with vitamin B12 deficiency [9]