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These actions are beneficial in preventing and treating autoimmune diseases, dampening allergic responses, and reducing rejection following blood and marrow and solid organ transplantation (145, 146)

The ratio is useful for controlled comparisons but is not a complete thermodynamic description of redox state

However, the presence of ulcers, bleeding, and an imbalance in the mucosal environment can further compromise the integrity of the intestinal mucosal barrier, ultimately resulting in a detrimental cycle of ongoing mucosal damage and destruction, impaired reconstruction capacity, and exacerbated homeostatic imbalance (Chang et al., 2013)

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Azacitidine is the first epigenetic drug approved by the FDA for the treatment of cancer (Myasoedova et al., 2019)

Hyperpigmentation of the skin, caused by an increase in melanin, is usually seen as aesthetically unfavorable