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2026;14(2):e70340

The decreased cell surface area to volume ratio and increased cell sphericity with attendant increased osmotic fragility observed in HS erythrocytes are accompanied by externalization of phosphatidylserine (1, 35)

While hydroquinone has long been considered the gold standard for treating hyperpigmentation, several alternatives offer effective results with different benefits and limitations

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The benefits of these various delivery methods can offer convenience and much more, but bioavailability must be taken into account by researchers