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Historical Background and Scientific Context Mitochondrial-derived peptides emerged as an important area of scientific research following the discovery that mitochondrial DNA encodes biologically active peptides capable of participating in intracellular signalling networks

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20% of NB patients and drives half of the aggressive forms of the disease with poor outcomes ( MYCN transcriptional machinery, synthetic lethality, and destabilization of the MYCN protein (6, 7)

Cognitive impairment in myocardial infarction and heart failure

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For example, if you have a deficiency and need regular B12 injections, hydroxocobalamin can be given once every 3 months, whereas cyanocobalamin would need to be given every month