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MOTSc is studied in preclinical models to better understand metabolic signaling (how cells coordinate energy use), cellular energy regulation (how cells respond when energy demand changes), and mitochondrial homeostasis (how mitochondria maintain stable function)

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Experimental data indicate that even brief exposure (e.g., 7 days) can result in a marked increase in sperm morphological abnormalities ( Figure 1a )

Mekiten O, Yitzhaky A, Gould N, Rosenblum K, Hertzberg L

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