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In addition, a moderately augmented level of ROS induces the expression of genes coding for these antioxidant enzymes and redox-regulated chaperones 12

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iNOS dimerization then leads to the accumulation of cellular NO, which subsequently results in the accumulation of cellular ROS and lipid peroxides as well as mitochondrial ROS and lipid peroxides, and ultimately, oxidative ferroptosis

1,4 Painful DN, often associated with SFN, occurs in approximately 25% of diabetes patients and significantly impacts the quality of life due to chronic pain and sensory disturbances

Effects of lactobacillus plantarum and lactobacillus paracasei on the peripheral immune response in children with celiac disease autoimmunity: A randomized, double-blind, placebo-controlled clinical trial