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difficile cause increased morbidity and mortality, as these infections can be refractory to antimicrobial therapy and may require colectomy

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Suspected adverse reactions can be reported to the FDA MedWatch program at www.fda.gov/medwatch or by calling 1-800-FDA-1088

Intriguingly, despite the striking similarity in suramin-binding sites between the EBOV and MARV polymerases, suramin showed significantly lower binding affinity for the MARV polymerase compared to the EBOV polymerase

This includes provisions for the application process related to increased applicable percentages and dispute resolution