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GAT-1 maintains the homeostasis of inhibitory neuronal microcircuits, and its functional or expression abnormalities are closely associated with the development of various neurological disorders, including autism, schizophrenia, and epilepsy ( 3.2.2 The Interaction between GABA and Its Receptors GABA signaling transduction is mediated by membrane-bound receptors, primarily involving two major types: GABAA and GABAB receptors

This system outperformed Dex cream or tacrolimus ointment in treatment efficacy

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It is shown that IGFBP1 expression and secretion were significantly elevated in cancer cells, and secreted IGFBP-1 inhibits AKT1-mediated phosphorylation of ser27 of mitochondrial superoxide dismutase 2 (SOD2), thereby increasing the activity of SOD2 antioxidant enzymes

The brain sections were floated in 0.01 M PBS and stored at 4 C until use

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