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SKU: 84990174807
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Beyond these, several special conditions amplify the ROS burden: : Excess hepatic iron (as in hereditary hemochromatosis or iron overload due to excessive red blood cell transfusions) catalyzes the Fenton reaction (FeIron overload 2 + H 2 O 2 Fe 3 + OH + OH), generating highly reactive hydroxyl radicals

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We found that NOX2-mediated O 2 - overproduction was mainly located in the vasculature and endothelium, which induced reactive glial cell proliferation that mediated neuroinflammation and iBRB injury