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However, it is unclear whether TDP-43 is a direct target of SUMO2 and what the implications are on TDP-43 function and disease pathogenesis

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doi: 10.1016/S0014-5793(97)00499-7

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Intestinal permeability test Mice were orally administered 0.5 mL of 25 mg/mL 4 kDa fluorescein isothiocyanate (FITC)-dextran (Merck, 46,944) in sterile water 30 min prior to sacrifice