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[42] Although initial symptoms may vary, most patients develop skeletal muscle weakness that progresses to involve the entire body

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In one well, we first determined the cell viability by fluorescence measurement, and then after removing the culture medium, lysing the cells, and adding the substrates, we measured the luminescence signal in individual samples

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We observed the most concentrated enrichment among oxidative phosphorylation enzymes, the citric acid cycle, and fatty acid oxidation