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A protein-protein interaction (PPI) network was constructed, revealing 16 genes with significantly altered expression levels (Fig

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Puerarin suppresses macrophage M1 polarization to alleviate renal inflammatory injury through antagonizing TLR4/MyD88-mediated NF-B p65 and JNK/FoxO1 activation

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ROS (such as superoxide anion, hydrogen peroxide, and hydroxyl radicals) are produced by activated immune cells as part of the respiratory burst that kills pathogens [16]

Beads were then washed three times with ice-cold 1 PBS, and bound proteins were eluted for subsequent mass spectrometry (MS) analysis as described below