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The pattern of AEs was as expected and all resolved by study end

The menace within: bacterial amyloids as a trigger for autoimmune and neurodegenerative diseases

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continued using Bmal1 knockout mice and reported altered clock gene expression (Cry2 and Per2) along with decreased Nrd1, Dbp, Il1 , and Nox2 expression and increased Gsr and Lpl expression, indicating that Bmal1 regulates immune response and cellular metabolism in microglia (Wang et al., 2020)

Claims data have inherent limitations: 1) There may be coding errors and missing data 2) Lack of data on reason for discontinuation 3) ICD-10 codes do not identify patients by MS subtypes

Therefore, the transporter protein does not function properly