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When there is an increase in melanin production, the skin develops dark patches, which can be of different shapes, sizes, and colors

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Plates were sealed with sterile CyclerSeal (Axygen, USA) and incubated at 25C

Meanwhile, the multifaceted roles of nutraceuticals, including polyphenols, vitamins, and the Mediterranean diet, in modulating oxidative stress, neuroinflammation, and mitochondrial dysfunction have been extensively studied (Soni et al., 2024)