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Discussion Overall, BaP as the product of combustion of organic matter including fossil fuels, can pollute the environment

The exact mechanism that governs the routing of cysteine toward glutathione or methionine during stresses remains unclear

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Strikingly, sporadic mutation of equivalent arginine residues in the HRD motifs of unrelated protein kinases are similarly catastrophic and cause rare, monogenic forms of various human diseases [145,146,147,148,149]

Jacque N, Ronchetti AM, Larrue C, Meunier G, Birsen R, Willems L, Saland E, Decroocq J, Maciel TT, Lambert M, Poulain L, Hospital MA, Sujobert P, Joseph L, Chapuis N, Lacombe C, Moura IC, Demo S, Sarry JE, Recher C, Mayeux P, Tamburini J, Bouscary D