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( f ) Number of CD38 + cells by flow cytometry was measured in spleen and jejunum with and without LPS treatment (n=5 mice per group)

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For stronger data integrity, studies should include suitable controls, repeat measurements, documented acceptance criteria, and a clear distinction between exploratory findings and validated conclusions

Our findings demonstrate that senescence-induced inflammation promotes accumulation of CD38 in immune cells that, through its ecto-enzymatic activity, decreases levels of NMN and NAD +

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