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In humans, theres no published answer, because no human efficacy trial exists yet

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However, significant or lasting weight loss should be attributed to lifestyle changes and metabolic improvements , not the injections alone

A talk someone posted recently by a doctor mentions that he treats patients with methylfolate and not folic acid

While there is no established link between these medications and structural changes to taste buds themselves, the functional experience of taste can be significantly modified during treatment, impacting dietary preferences and eating behaviors in ways that may contribute to the therapeutic effects of these agents