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Atherosclerosis 269, 306311

High glucose levels can cause macrophage infiltration, the activation of NOX1-PKC signaling, and mitochondrial dysfunction, culminating in increased ROS levels and senescence of endothelial cells

Plasma amino acid concentrations were determined by ion exchange HPLC

Abbreviations HIF: Hypoxia inducible factor GSH: Glutathione Ac-LDL: Acetylated low-density lipoprotein GSEA: Gene set enrichment analysis DE: Differentially expressed (genes) References Meir JU, Champagne CD, Costa DP, Williams CL, Ponganis PJ

The G6PD in this species is unique in that it has no cysteine/cysteine residues and has an essential lysine at the active site

Loss of caspase-8 in hepatocytes accelerates the onset of liver regeneration in mice through premature nuclear factor kappa B activation