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10.1016/j.tice.2021.101612 34 ImenshahidiM.HosseinzadehH

After the association phase, buffer is passed over the chip and the rate of dissociation of antibody (k off ) determined

The maximum dose is typically reached around week 21-24

If a decision is made to treat serious respiratory depression in the physically dependent patient, administration of the antagonist should be initiated with care and by titration with smaller than usual doses of the reversal agent

Another common measure looks at daytime sleepiness rather than nighttime sleep quality

Allergic reactions: Allergic reactions including anaphylaxis have been reported with diclofenac and glucocorticoids