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These findings underscore the adverse effects of mercury toxicity on vital organs, leading to physiological and metabolic disruptions in fish.\ Mercury determination through ICP-MS The mercury levels in the experimental water and various fish tissues (muscle, liver, gills, and kidney) are presented in Table 6

In- vivo study suggested that, prophylactic inhibition of catecholamine synthesis by a tyrosine hydroxylase antagonist- metyrosine, reduced levels of catecholamines and cytokine responses and resulted in markedly increased various inflammatory stimuli in mice

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( Mendeley Data)

and (3) a milder riboflavin responsive myopathic phenotype with exertional fatigue, intermittent elevation of blood lactate, ketoacidosis, creatine kinase, and mitochondrial proliferation [143,145,146]

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