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Furthermore, SAM is a precursor in the synthesis of melatonin and is also an enzymatic cofactor of glutathione production [29]

Nov 12 2014;25(16):1250-4

Infusing water alone (a hypotonic solution) into the bloodstream can cause hemolysis destruction of red blood cells due to osmotic imbalance

The abdomen (avoiding a 2-inch radius around the navel), outer thigh, and upper arm provide suitable injection locations with adequate subcutaneous tissue