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Materials and Methods Hydrogel Substrate Preparation and Optical Setup for H 2 O 2 Detection In order to perform time-lapse detection of H 2 O 2 secreted from living cells cultured in different formats, a hydrogel-based substrate capable of generating optical spectrum shift while reacting with H 2 O 2 due to LSPR and enzyme immunoprecipitation is exploited in the experiments as shown in Figure 1A

Upregulated and downregulated metabolites in drug-resistant strain are indicated with red and blue, respectively

I mean, it's like one thing in movie theater, because the movie, the actors on screen can't see you, but I do think that's rude too

doi: 10.1016/j.apsb.2023.03.001 55 XuXJWanTXinHHLiDPanHMWuJet al

Additionally, it stimulates the Na + -K + -ATPase enzyme, contributing to the overall modulation of sleep mechanisms

keep the reconstituted solution refrigerated and use within a few weeks