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Suppression of IL-10/STAT3 or TGF-/SMAD-dependent antioxidant circuits enables the restoration of lipid peroxidation susceptibility in adjacent tumor cells (107)

Adeno-associated virus: fit to serve

[DOI] [PubMed] [Google Scholar] 75.Ringe D, Petsko GA

It induces the production of ROS and activates mitochondrial kinase GSK3-/, leading to the opening of the mitochondrial permeability transition pore (MPTP) (Weidner et al., 2016)