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Clinical indications of cholestasis (discoloured faeces, dark urine) frequently occur in the first few months of infancy (with a tendency to appear earlier than PFIC1), with recurring or persistent jaundice, low GT, elevated BAs and FP, hepatomegaly, and severe pruritus

1mg weekly dose The lowest dose tested

The test involves incubating product samples in growth media (typically Fluid Thioglycollate Medium for bacteria and Soybean-Casein Digest Medium for fungi) for a minimum of 14 days and observing for microbial growth

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But even a pure form of a drug that hasnt been through rigorous testing isnt necessarily a safe one