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Yan LS, Zhang SF, Luo G, Cheng BC, Zhang C, Wang YW, et al

PARP inhibitors , including olaparib and niraparib , impair DNA repair in BRCA-mutated cells and are approved for ovarian, breast, pancreatic, and prostate cancers

In addition to thiosemicarbazone derivatives, thiosemicarbazide and its derivatives 378381 , 5-benzylidene(thio)barbiturate-beta-d-glycosides 382 , n -alkyl 383 , p -phenylene-bis, phenyl 384 , benzyl, p -xylidine-bis and p -pyridine dithiocarbamate sodium salts 385 , diethyldithiocarbamate, phenylthiourea 3 86 and other thiourea derivatives (Figure 12) such as methimazole, thiouracil, methylthiouracil, propylthiouracil, ambazone, and thioacetazone 387 have been identified as tyrosinase inhibitors

Accessed 06 Sept 22

The most notorious function of mitochondria, which is to oxidize various nutrients such as fat and carbohydrate via a series of complex chemical reactions to create the basic energy unit ATP

Cristina Mathewman, PhD