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Moreover, receptor kinase has been recently shown to sense H 2 O 2 at the plasma membrane and to activate signaling cascades (Wu et al., 2020)

The nitric oxide radical (NO) gives rise to reactive nitric oxide species (RNOS) and reacts with superoxide anion (O 2 ) to form the peroxynitrite radical (ONOO ), which is reduced to nitrite and nitrate (NO 3 ) 26,27

Applied in different protocols, NaBPC157 was shown to decrease the number of metastases in treated mice relative to corresponding controls