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If youre not deficient, routine injections are seldom necessary

While more human data is needed, its mechanism aligns with many principles of functional and longevity medicine namely, supporting mitochondria, reducing inflammation, and improving insulin sensitivity

Supplements can still be effective, especially if you're looking to maintain your B12 levels over time

Strong evidence, from decades of treating individuals with inborn errors of B 12 metabolism, supports the safety of parenteral, lifelong, even high dose hydroxocobalamin, sometimes even at very high doses

"Proton pump inhibitor and histamine 2 receptor antagonist use and vitamin B12 deficiency"

AMPK activation and fat browning This is where the science gets genuinely exciting