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In 3xTg-AD mice, dietary SAMe supplementation reduced hippocampal A and phosphorylated tau, and delayed the accumulation of extracellular A, demonstrating SAMes ability to modulate the time course of AD neuropathology (21, 23)

Wilson KT, Crabtree JE

Metabolites 13 , 1006 (2023)

A nutritious diet supports production, but supplementation helps bridge the gap during periods of stress or high environmental exposure.

The last one is L-cysteine, which is used to regenerate or reduce the oxidized form of L-glutathione in the eye

The Energy and Cognitive Complex B-vitamins specifically B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), and B6 (pyridoxine) are essential cofactors in cellular energy production