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Early studies suggest Epithalon may restore melatonin rhythmicity and reduce oxidative stress markers, though independent replication at scale is lacking

10.1016/j.tranon.2025.102513 48 SongG.XueS.ZhuY.WuC.JiX

Subclinical cerebrovascular disease: Epidemiology and treatment

Collectively, these results suggested that APR-017 and LCS3 treatment induce vulnerability of VRK2-deficient PC cells by GSH inhibition and consequent disruption of the balance between ROS generation and antioxidation