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Store in the patients permanent clinical file with treatment date, batch/lot number, and post-injection observations

Crowell PD, Goldstein AS

Tirzepatide, a dual GIP and GLP-1 receptor agonist approved by the FDA for type 2 diabetes (Mounjaro) and chronic weight management (Zepbound), may indirectly affect menstrual cycles in some women

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Occurrences of thrombocytopenia with thrombosis that manifested similar to heparin- induced thrombocytopenia have been reported in the postmarketing experience and cases of elevated aPTT temporally associated with bleeding events have been reported following administration of fondaparinux sodium (with or without concomitant administration of other anticoagulants) [see Warnings and Precautions (5.5)]

A total of 1,725 patients were enrolled with 862 patients randomized to pemetrexed in combination with cisplatin and 863 patients to gemcitabine in combination with cisplatin