More serousB12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serous symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia, and changes in reflexes
2014;134:e700e9
Proteomics data are available via ProteomeXchange with the identifier PXD042314 ( Abbreviations ASD: autism spectrum disorders CNS: central nervous system CGI: Clinical Global Impression DEGs: differentially expressed genes DEPs: differentially expressed proteins EV: extracellular vesicles FC: fold change GCP: Good Clinical Practice GO-BP: Gene Ontology-Biological Process GSEA: Gene Set Enrichment Analysis IRB: Institutional Review Board LR: ligandreceptor LCMS/MS: liquid chromatography tandem mass spectrometry MCID: minimal clinically important difference NK: natural killer NTA: nanoparticle tracking analysis PBMCs: peripheral blood mononuclear cells PBS: phosphate-buffered saline PD: Proteome Discoverer pDCs: Plasmacytoid dendritic cells PHGDH: Phosphoglycerate dehydrogenase SEM: standard error of the mean TADA: Transmission and de novo Association WGCNA: Weighted gene co-expression network analysis References Maenner, M
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Standardization represents a critical determinant of Rhodiolas reproducibility and clinical efficacy
