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Research in individuals with hypothyroidism and experimental studies involving hormone replacement propose that thyroxine administration may enhance the response to GRF stimulation

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Methylation is necessary for many key biochemical reactions in the body, including: Detoxification (including estrogen and endocrine disruptor detoxification) Neurotransmitter production Genetic expression (more on this below) Amino acid (protein) metabolism Growth and development (including pregnancy) Producing phosphatidylcholine for cell membranes Producing creatine for muscle health and strength Producing glutathione for antioxidant protection The methylation process requires specific nutrients to produce methyl groups