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Wuhan Univ

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sativa has a therapeutic effect by reducing cytotoxicity, oxidative stress, inflammatory response and cell death caused by mitochondrial dysfunction in keratinocyte cells irradiated with ultraviolet A (UVA) light (10)

The on-off switches of the mitochondrial uncoupling proteins

doi: 10.1038/nn.3144

Concurrently, elevated renal venous pressurestemming from right ventricular dysfunction or tricuspid regurgitationand angiotensin II-mediated efferent arteriolar constriction reduce the glomerular filtration rate (GFR), fostering glomerulosclerosis and tubular atrophy, which are hallmarks of acute kidney disease (AKD) and chronic kidney disease (CKD)