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The BPOM-approved product information also lists known adverse effects and warnings, including common gastrointestinal side effects like nausea, vomiting, diarrhea, constipation, and abdominal pain

4-OHE2 quinones are highly reactive electrophiles that form depurinating DNA adducts covalently bonding to adenine and guanine bases in DNA and triggering their removal from the DNA backbone

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Structure and Pharmacology BPC-157 consists of 15 amino acids with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

Functional imaging studies have reported decreased activation of caudate, putamen, thalamus, and globus pallidus in bipolar patients performing a response inhibition task, and attenuated ventral striatum responses to happy faces across the mood states (90)

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