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Description

J Biol Chem 2015;290:2312434

Abils J, Prez de la Cruz A, Castao J, Rodrguez Elvira M, Aguayo E, Moreno-Torres R y cols

MLKL drives basal resistance to ferroptosis by depleting PUFAs, whereas ACSL4 promotes basal resistance to necroptosis by making the membrane less susceptible to MLKL-driven permeabilization [16, 214]

Sci Rep 4:6328

In summary, this review seeks to establish a comprehensive and multidimensional model of neutrophil regulation, providing new perspectives for potential clinical applications and further research

By combining both peptides in a single formulation, researchers can study potential synergistic interactions without the complexity of sourcing, reconstituting, and administering two separate compounds