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doi: 10.1210/er.2013-1029 31 BancosIHahnerSTomlinsonJArltW

Resveratrol as a modulator of the circadian rhythm in various diseases Metabolic disorders Circadian rhythm misalignment can lead to various metabolic disorders such as dyslipidemia, hyperglycemia, insulin resistance, obesity and diabetes [7, 8]

Despite the availability of current therapeutic options, including phosphate binders and vitamin D analogs, these treatments fall short in adequately addressing the immune-mediated aspects of CKD-MBD, indicating an urgent need for innovative strategies that effectively target inflammatory pathways, inhibit sclerostin, or modulate fibroblast growth factor (FGF)-23 levels

To further evaluate the potential of MH and SP as drug candidates for PD treatment, we also examined their effects on PD-like behavior traits in a mouse model induced by ROT, a known cause of motor function abnormalities