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For an ACO that reports all of the required measures in the APP Plus quality measure set, meeting the data completeness requirement at 414.1340 of this subchapter for all of the required measures in the APP Plus quality measure set, and administers the CAHPS for MIPS survey (except as specified in 414.1380(b)(1)(vii)(B) of this subchapter), CMS calculates the ACO's health equity adjusted quality performance score as the sum of the ACO's MIPS Quality performance category score for all measures in the APP Plus quality measure set and the ACO's health equity adjustment bonus points calculated in accordance with paragraph (b)(4) of this section

Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women

We proposed in the CY 2025 PFS proposed rule to include the performance measurement requirement as an element of APCM services furnished by practitioners, see section II.G.2.c

Thymosin beta-4 in a rat medial collateral ligament model

Larger population studies would be needed to identify uncommon reactions