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A single pass of a serum or cell-lysate sample through an affinity column can achieve greater than 1000-fold purification of a specific protein so that only a single band is detected after gel electrophoresis (e.g., SDS-PAGE) analysis

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However, to date, there are no FDA-approved treatments available for all patients with ALD, especially those who will ultimately develop one of the ALD phenotypes in the later decades of life

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The project was directed by MR and HFN who also wrote the manuscript

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